Is Key West Safe for Cruise Passengers?
Key West is rated low risk for cruise travelers. Most visitors experience the port without incident when they use licensed transportation and stay in established tourist and port areas.
See the current cruise safety outlookAt a Glance
Executive Summary
Key West is the southernmost city in the continental U.S. and one of the most charming cruise stops in Florida. Known for its laid-back Conch Republic culture, Duval Street nightlife, Hemingway House, and the only living coral reef in the continental U.S., it’s a Caribbean experience with American conveniences.
Quick Facts
Risk Level
Low
Country
United States (Florida)
Currency
U.S. Dollar (USD)
Language
English
Emergency Number
911
Best Time to Visit
November–April (cooler, drier)
Cruise Port
Mallory Square Pier & Pier B, Key West
Nearest Hospital
Lower Keys Medical Center, Stock Island
Vaccines
No special vaccines required; mosquito repellent advised
Health Considerations
Safety & Security
Local Emergency Number
911
Store this number in your phone before going ashore.
Frequently Asked Questions
Is Key West safe for cruise passengers?+
Can I drink the tap water in Key West?+
What is Key West famous for?+
Is there a travel warning for Key West?+
Is it safe to leave the cruise port in Key West?+
What health risks should cruise passengers know about in Key West?+
Source Citations & Review History
Our medical and travel experts synthesize information from the following authoritative public sources. We do not rely on AI without human verification.
- CDC Travelers’ Health — United States— CDC
- U.S. State Department — United States— U.S. State Department
Related Intelligence
Preparedness Checklist
Review Skip's "Before You Sail" tips and the CDC's traveler recommendations so you board prepared.

